Longitudinal Changes in Body Weight of Breastfeeding Mothers in the First Year after Delivery and its Relationship with Human Milk Composition: a Combined Longitudinal and Cross-sectional Cohort Study

Objective Postpartum weight retention (PPWR), which refers to the value of postpartum minus pre-pregnancy weight, is a common problem among women after childbirth. The main objectives this study are understand changes in body breastfeeding mothers during long-term follow-up and preliminarily explore relationship between maternal human milk composition, including macronutrients, leptin, adiponectin. Methods included longitudinal cohort [122 mothers], cross-sectional [37 mothers]. milk, dietary surveys were collected at different time points (1-14 days postpartum, 2-4 months 5-7 12-17 postpartum). was analyzed using responses survey questionnaires. A analyzer based on mid-infrared spectroscopy (MIRS) used determine nutrition analysis software evaluated intakes. In cohort, participating asked provide blood samples pertinent information related composition. Maternal composition measured by bioelectrical impedance (BIA), while ELISA leptin adiponectin serum. Results At PPWR 2.46 ± 3.59kg. 0.98 4.06kg. found be negatively correlated with fat content within 14 positively postpartum. addition, muscle mass milk. Plasma mother's BMI, FAT%, mass, plasma did not correlate any parameter. results also indicate that or Conclusions Breastfeeding may retain considerable gain one year delivery. Human weight. Leptin breast associated This supports notion nutritional status affect offspring health through lactation, future research should focus exploring management mothers.